Cajun Shrimp Alfredo Lasagna (Print Version)

Spicy shrimp and creamy Alfredo layered with pasta and cheese for an irresistible, bold main course.

# Components:

→ Seafood

01 - 1 pound large shrimp, peeled and deveined
02 - 1 tablespoon Cajun seasoning

→ Pasta

03 - 9 no-boil lasagna noodles, or regular noodles cooked per package instructions

→ Vegetables

04 - 1 medium onion, finely chopped
05 - 3 cloves garlic, minced
06 - 1 red bell pepper, diced
07 - 1 cup baby spinach, roughly chopped

→ Alfredo Sauce

08 - 4 tablespoons unsalted butter
09 - 3 cups heavy cream
10 - 1 cup freshly grated Parmesan cheese
11 - 1 cup shredded mozzarella cheese
12 - 1/2 teaspoon black pepper
13 - 1/2 teaspoon salt
14 - Pinch ground nutmeg

→ Cheese

15 - 1 1/2 cups shredded mozzarella cheese, for layering
16 - 1/2 cup grated Parmesan cheese, for topping

→ Garnish

17 - Chopped fresh parsley, optional

# Method:

01 - Preheat the oven to 375°F (190°C).
02 - Toss the shrimp with Cajun seasoning until thoroughly coated.
03 - Melt 1 tablespoon butter in a large skillet over medium-high heat. Add shrimp and cook for 2 to 3 minutes per side, until just opaque. Transfer shrimp to a plate and set aside.
04 - Add remaining butter to the skillet. Sauté onion and red bell pepper for 3 to 4 minutes, until softened. Add garlic and cook for 1 additional minute.
05 - Pour in heavy cream and bring to a gentle simmer. Reduce heat to low, then whisk in Parmesan cheese, mozzarella cheese, salt, black pepper, and a pinch of nutmeg. Stir until the sauce is smooth and thickened, about 3 to 5 minutes.
06 - Set aside 1 cup of Alfredo sauce for the topping.
07 - Spread a thin layer of Alfredo sauce in the base of a 9x13-inch baking dish. Arrange 3 lasagna noodles over the sauce. Layer one-third of the remaining Alfredo sauce, one-third of the shrimp, one-third of the spinach, and one-third of the mozzarella cheese evenly over the noodles. Repeat the layering process two more times.
08 - Pour reserved Alfredo sauce over the top layer. Sprinkle with grated Parmesan cheese.
09 - Cover the dish with foil and bake for 25 minutes.
10 - Remove foil and continue baking for 15 to 20 minutes, until the top is bubbling and golden brown.
11 - Allow to rest for 10 to 15 minutes before slicing. Garnish with chopped parsley if desired.

# Expert Advice:

01 -
  • Rich creamy Alfredo sauce and spicy Cajun shrimp make every bite exciting
  • Great for pescatarians or anyone wanting a fresh spin on classic lasagna
  • No-boil noodles save time and make assembly simple
  • Customizable add-ins for heat or extra protein to suit every palate
  • Layers beautifully for showstopping presentation and leftovers taste even better the next day
02 -
  • Layers of cheese pasta and Cajun shrimp create the ultimate comfort food experience
  • Packed with protein from shrimp and extra veggies for balance
  • Makes six hearty servings with leftovers keeping flavor and texture
03 -
  • Use freshly grated cheese so your sauce stays super creamy and layer melts perfectly
  • Do not skimp on resting time after baking because hot lasagna slices always fall apart if rushed
  • For spicier flavor mix a little extra Cajun seasoning into the Alfredo before building layers but taste as you go so it never overpowers the shrimp

Return